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CDK2AP1 (基因名), Cyclin-dependent kinase 2-associated protein 1 (蛋白名), cdka1_human.
产品名称:

Human CDK2AP1/ Cyclin-dependent kinase 2-associated protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Deleted in oral cancer 1, Putative oral cancer suppressor, DOC-1, CDK2-associated protein 1, CDKAP1, DOC1

序列号:
O14519
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CDK2AP1 Protein
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Human CDK2AP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 12q24.31 by HGNC 12q24.31 by Entrez Gene 12q24.31 by Ensembl
CDK2AP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer (PubMed:22427660). Interacts with monomeric unphosphorylated CDK2 (By similarity). Interacts with CDK2AP2 (PubMed:14985111).


功能:
specific inhibitor of the cell-cycle kinase CDK2.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1."

[2].
"Isolation, mapping and mutation analysis of a human cDNA homologous to the doc-1 gene of the Chinese hamster, a candidate tumor suppressor for oral cancer."

[3].
"Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region."

[4].
"Interaction of the CDK2-associated protein-1, p12(DOC-1/CDK2AP1), with its homolog, p14(DOC-1R)."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Differential expression of DOC-1 in microsatellite-unstable human colorectal cancer."

[7].
"Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells."

[10].
"p12CDK2-AP1 interacts with CD82 to regulate the proliferation and survival of human oral squamous cell carcinoma cells."
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