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CD68 (基因名), Macrosialin (蛋白名), cd68_human.
产品名称:

Human CD68/ Macrosialin Recombinant Protein
巨噬唾液酸蛋白

货号:

R2303h

商标:
EIAab®
监管等级:
别名:

Gp110, CD68

序列号:
P34810
来源:
E.coli
种属:
Human
标签:
His
序列:
48-164aa
预估分子量:
12.87 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CD68 Protein
规格 & 价格: cart
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Human CD68 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human CD68 Protein
Recombinant human CD68 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 17p13.1 by HGNC 17p13.1 by Entrez Gene 17p13.1 by Ensembl
CD68 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.


亚细胞位置:
Isoform Long Endosome membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13."

[2].
"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."

[3].
"Granular cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical correlation."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"Macrophage/histiocytic antigen CD68 expression in neoplastic and reactive lymph nodes."

[6].
"Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner."

[7].
"[The "classical" macrophage marker CD68 is strongly expressed in primary human fibroblasts]."

[8].
"Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins."

[9].
"Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma."

[10].
"The role of macrophages in the differentiation process of ureteral polyps."
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