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CCL3 (基因名), C-C motif chemokine 3 (蛋白名), ccl3_human.
产品名称:

Human CCL3/ C-C motif chemokine 3 Recombinant Protein
C-C模体趋化因子3

货号:

R0092h

商标:
EIAab®
监管等级:
别名:

G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, PAT 464.1, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha, G0S19-1, MIP1A, SCYA3

序列号:
P10147
来源:
E.coli
种属:
Human
标签:
His
序列:
24-92aa
预估分子量:
7.59 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
  • Human CCL3 Protein
  • Human CCL3 Protein
  • Human CCL3 Protein
规格 & 价格: cart
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Human CCL3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human CCL3 protein including hydrophilcity, hydrophobicity and antigenicity.
Human CCL3 Protein
Recombinant human CCL3 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 17q12 by HGNC 17q12 by Entrez Gene 17q12 by Ensembl
CCL3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69).


功能:
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Identification of new variants within the two functional genes CCL3 and CCL3L encoding the CCL3 (MIP-1alpha) chemokine: implications for HIV-1 infection."

[2].
"Association between the macrophage inflammatory protein-l alpha gene polymorphism and Alzheimer's disease in the Chinese population."

[3].
"CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection."

[4].
"Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants."

[5].
"Structures of human genes coding for cytokine LD78 and their expression."

[6].
"Three human homologs of a murine gene encoding an inhibitor of stem cell proliferation."

[7].
"Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment."

[8].
"Genome-wide haplotype association analysis and gene prioritization identify CCL3 as a risk locus for rheumatoid arthritis."

[9].
"TLR activation pathways in HIV-1-exposed seronegative individuals."

[10].
"HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes."
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