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BSN (基因名), Protein bassoon (蛋白名), bsn_human.
产品名称:

Human BSN/ Protein bassoon Recombinant Protein
Bassoon蛋白

货号:

R12516h

商标:
EIAab®
监管等级:
别名:

Zinc finger protein 231, KIAA0434, ZNF231

序列号:
Q9UPA5
来源:
E.coli
种属:
Human
标签:
His
序列:
1-270aa
预估分子量:
29.7 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human BSN Protein
规格 & 价格: cart
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Human BSN Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human BSN Protein
Recombinant human BSN protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p21.31 by HGNC 3p21.31 by Entrez Gene 3p21.31 by Ensembl
BSN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with ERC2/CAST1, RIMS1 and UNC13A. Part of a complex consisting of ERC2, RIMS1 and BSN.


功能:
Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses.


亚细胞位置:
Cytoplasm Cell junction Synapse Synaptosome Cytoplasm Cytoskeleton Localized to the active zone of presynaptic density.


该产品尚未在任何出版物中被引用。

[1].
"The presynaptic cytomatrix protein Bassoon: sequence and chromosomal localization of the human BSN gene."

[2].
"Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy (MSA)."

[3].
"Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population."

[4].
"Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease."

[5].
"Association analysis of 3p21 with Crohn's disease in a New Zealand population."

[6].
"Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study."

[7].
"Genetic risk profiling and prediction of disease course in Crohn's disease patients."

[8].
"Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept."

[9].
"Effect of BSN-MST1 locus on inflammatory bowel disease and multiple sclerosis susceptibility."

[10].
"Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region."
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