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BPI (基因名), Bactericidal permeability-increasing protein (蛋白名), bpi_human.
产品名称:

Human BPI/ Bactericidal permeability-increasing protein Recombinant Protein
杀菌性通透性增加蛋白

货号:

R1234h

商标:
EIAab®
监管等级:
别名:

CAP 57, BPI

序列号:
P17213
来源:
E.coli
种属:
Human
标签:
His
序列:
194-359aa
预估分子量:
18.26 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human BPI Protein
规格 & 价格: cart
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Human BPI Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 20q11.23 by HGNC 20q11.23 by Entrez Gene 20q11.23 by Ensembl
BPI Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer. Homodimer; disulfide-linked.


功能:
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.


亚细胞位置:
Secreted Cytoplasmic granule membrane Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.


该产品尚未在任何出版物中被引用。

[1].
"Polymorphisms in the lipopolysaccharide-binding protein and bactericidal/permeability-increasing protein in patients with myocardial infarction."

[2].
"Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution."

[3].
"Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation."

[4].
"Genetic susceptibility to distinct bladder cancer subphenotypes."

[5].
"Circulating bactericidal/permeability-increasing protein (BPI) is associated with serum lipids and endothelial function."

[6].
"Risk of meningioma and common variation in genes related to innate immunity."

[7].
"Polymorphisms in innate immunity genes and risk of childhood leukemia."

[8].
"Role of polymorphic variants as genetic modulators of infection in neonatal sepsis."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder."
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