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BCO2 (基因名), Beta,beta-carotene 9',10'-oxygenase (蛋白名), bcdo2_human.
产品名称:

Human BCO2/ Beta,beta-carotene 9',10'-oxygenase Recombinant Protein
β胡萝卜素双脱氧酶2

货号:

R10866h

商标:
EIAab®
监管等级:
别名:

B-diox-II, Beta-carotene dioxygenase 2, BCDO2

序列号:
Q9BYV7
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human BCO2 Protein
规格 & 价格: cart
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Human BCO2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 11q23.1 by HGNC 11q23.1 by Entrez Gene 11q23.1 by Ensembl
BCO2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.


亚细胞位置:
Mitochondrion


该产品尚未在任何出版物中被引用。

[1].
"Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues."

[2].
"Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A."

[3].
"A mitochondrial enzyme degrades carotenoids and protects against oxidative stress."

[4].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[5].
"Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels."

[6].
"A genome-wide association study identifies protein quantitative trait loci (pQTLs)."

[7].
"Towards a better understanding of carotenoid metabolism in animals."

[8].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[9].
"Mitochondrial β-Carotene 9',10' Oxygenase Modulates Prostate Cancer Growth via NF-κB Inhibition: A Lycopene-Independent Function."

[10].
"Molecular aspects of β, β-carotene-9', 10'-oxygenase 2 in carotenoid metabolism and diseases."
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