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BAK1 (基因名), Bcl-2 homologous antagonist/killer (蛋白名), bak_human.
产品名称:

Human BAK1/ Bcl-2 homologous antagonist/killer Recombinant Protein
Bcl-2同源拮抗剂/杀伤细胞

货号:

R9626h

商标:
EIAab®
监管等级:
别名:

Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7, BAK, BCL2L7, CDN1

序列号:
Q16611
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human BAK1 Protein
规格 & 价格: cart
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Human BAK1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 6p21.31 by HGNC 6p21.31 by Entrez Gene 6p21.31 by Ensembl
BAK1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts with vaccinia virus protein F1 (PubMed:16439990). Interacts with myxoma virus protein M11L (PubMed:17386268).


功能:
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.


亚细胞位置:
Mitochondrion membrane Single-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak."

[2].
"BAK, BAX, and NBK/BIK proapoptotic gene alterations in Iranian patients with ataxia telangiectasia."

[3].
"Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis."

[4].
"Induction of apoptosis by the Bcl-2 homologue Bak."

[5].
"PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer."

[6].
"Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop."

[7].
"A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans."

[8].
"Human Bop is a novel BH3-only member of the Bcl-2 protein family."

[9].
"Genetic susceptibility to distinct bladder cancer subphenotypes."

[10].
"Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma."
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