EIAab
首页  >  重组蛋白  >  Human BAHD1 Recombinant Protein
BAHD1 (基因名), Bromo adjacent homology domain-containing 1 protein (蛋白名), bahd1_human.
产品名称:

Human BAHD1/ Bromo adjacent homology domain-containing 1 protein Recombinant Protein

货号:

R7589h

商标:
EIAab®
监管等级:
别名:

BAH domain-containing protein 1, KIAA0945

序列号:
Q8TBE0
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human BAHD1 Protein
规格 & 价格: cart
×
Human BAHD1 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 15q15.1 by HGNC 15q15.1 by Entrez Gene 15q15.1 by Ensembl
BAHD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with CBX5 (HP1 alpha), HDAC5, MBD1 and SP1. Forms a transcription silencing complex with at least CBX3 (HP1 gamma), HDAC1, HDAC2 and TRIM28. Interacts with L.monocytogenes LntA; this interaction, occurring at a late Listeria infection stage, relieves transcription repression, mostly that of interferon-stimulated genes.


功能:
Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon-stimulated genes, including IFNL1, IFNL2 and IFNL3.


亚细胞位置:
Nucleus Chromosome Localizes to heterochromatin and inactive X chromosome. Colocalizes with histone H3 trimethylated at 'Lys-27' (H3K27me3).


该产品尚未在任何出版物中被引用。

[1].
"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[2].
"A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response."

[3].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[4].
"Human BAHD1 promotes heterochromatic gene silencing."

[5].
"Architecture of the human interactome defines protein communities and disease networks."

[6].
"The BAH domain of BAHD1 is a histone H3K27me3 reader."

[7].
"Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism."

[8].
"Computational Prediction and Validation of BAHD1 as a Novel Molecule for Ulcerative Colitis."

[9].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[10].
"Structural basis for the inhibition of the chromatin repressor BAHD1 by the bacterial nucleomodulin LntA."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com