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B4GALT6 (基因名), Beta-1,4-galactosyltransferase 6 (蛋白名), b4gt6_human.
产品名称:

Human B4GALT6/ Beta-1,4-galactosyltransferase 6 Recombinant Protein
β-1,4-半乳糖基转移酶6

货号:

R5964h

商标:
EIAab®
监管等级:
别名:

Glucosylceramide beta-1, 4-galactosyltransferase, Lactosylceramide synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 6, UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 6, LacCer synthase, Beta-1, 4-GalTase 6

序列号:
Q9UBX8
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human B4GALT6 Protein
规格 & 价格: cart
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Human B4GALT6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 18q12.1 by HGNC 18q12.1 by Entrez Gene 18q12.1 by Ensembl
B4GALT6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:3099851, PubMed:1551920, PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity).


亚细胞位置:
Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Trans cisternae of Golgi stack.


该产品尚未在任何出版物中被引用。

[1].
"cDNA cloning and expression of human lactosylceramide synthase."

[2].
"The expanding beta 4-galactosyltransferase gene family: messages from the databanks."

[3].
"Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"Molecular cloning, genomic organization, and mapping of beta 4GalT-VIb, a brain abundant member of beta 4-galactosyltransferase gene family, to human chromosome 18q12.1."

[6].
"Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions."

[7].
"Architecture of the human interactome defines protein communities and disease networks."

[8].
"Evidence for disruption of sphingolipid metabolism in schizophrenia."

[9].
"Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus."

[10].
"VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo."
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