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ANPEP (基因名), Aminopeptidase N (蛋白名), ampn_human.
产品名称:

Human ANPEP/ Aminopeptidase N Recombinant Protein
氨肽酶N

货号:

R9154h

商标:
EIAab®
监管等级:
别名:

Alanyl aminopeptidase, Aminopeptidase M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, AP-M, CD13, AP-N, APN, CD13, PEPN

序列号:
P15144
来源:
E.coli
种属:
Human
标签:
His
序列:
739-967aa
预估分子量:
25.19 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human ANPEP Protein
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Human ANPEP Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ANPEP Protein
Recombinant human ANPEP protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 15q26.1 by HGNC 15q26.1 by Entrez Gene 15q26.1 by Ensembl
ANPEP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts with the S1 domain of human coronavirus 229E/HCoV-229E spike protein.


功能:
(Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein (PubMed:1350662, PubMed:8887485, PubMed:9367365, PubMed:12551991). Mediates as well human cytomegalovirus (HCMV) infection (PubMed:8105105).


亚细胞位置:
Cell membrane Single-pass type II membrane protein Also found as a soluble form.


该产品尚未在任何出版物中被引用。

[1].
"Expression of aminopeptidase N in human endometrium and regulation of its activity by estrogen."

[2].
"Molecular determinants of species specificity in the coronavirus receptor aminopeptidase N (CD13): influence of N-linked glycosylation."

[3].
"Modification of the amino terminus of a class II epitope confers resistance to degradation by CD13 on dendritic cells and enhances presentation to T cells."

[4].
"Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis."

[5].
"Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity."

[6].
"Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N."

[7].
"Characterization of functional domains in the human coronavirus HCV 229E receptor."

[8].
"Identification of an alanine aminopeptidase in human maternal serum as a membrane-bound aminopeptidase N."

[9].
"CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated."

[10].
"Cholesterol crystallization-promoting activity of aminopeptidase-N isolated from the vesicular carrier of biliary lipids."
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