首页 > 重组蛋白 > Human AGRP Recombinant Protein

AGRP (基因名), Agouti-related protein (蛋白名), agrp_human.

产品名称:

Human AGRP/ Agouti-related protein Recombinant Protein
刺鼠色蛋白相关蛋白

货号:

R1302h

商标:

EIAab^®

监管等级:

RUO

别名:

AGRT, ART

序列号:

O00253

来源:

E.coli

种属:

Human

标签:

His

序列:

21-132aa

预估分子量:

12.32 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human AGRP Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

Recombinant human AGRP protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 16q22.1 by HGNC 16q22.1 by Entrez Gene 16q22.1 by Ensembl

AGRP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Interacts with melanocortin receptors MC3R, MC4R and MC5R.

功能:

Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.

亚细胞位置:

Secreted Golgi apparatus lumen

数据库链接

UniGene:

Hs.104633

SMR:

O00253

STRING:

9606.ENSP00000290953

KEGG:

hsa:181

MIM:

601665

Pfam:

PF05039

Uniprot:

O00253

相关产品

Mouse Agrp ELISA Kit

Bovine AGRP ELISA Kit

Pig AGRP ELISA Kit

Mouse Agrp CLIA Kit

Bovine AGRP CLIA Kit

序列长度:

132

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

132:

CCDPCATCYC | RFFNAFCYCR | KLGTAMNPCS | RT

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Association between an agouti-related protein gene polymorphism and anorexia nervosa."

(PMID: 11326303)

[2].

"Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI."

(PMID: 19602223)

[3].

"Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset."

(PMID: 17197106)

[4].

"Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults."

(PMID: 16568137)

[5].

"The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors."

(PMID: 17041250)

[6].

"Melanocortin-4 receptor gene and physical activity in the Québec Family Study."

(PMID: 15597110)

[7].

"Two ethnic-specific polymorphisms in the human Agouti-related protein gene are associated with macronutrient intake."

(PMID: 16280444)

[8].

"Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans."

(PMID: 15054840)

[9].

"A polymorphism in the human agouti-related protein is associated with late-onset obesity."

(PMID: 12213871)

[10].

"Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children."

(PMID: 11487744)

[1].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人刺鼠色蛋白相关蛋白(AGRP)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人刺鼠色蛋白相关蛋白(AGRP)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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