首页 > 重组蛋白 > Human ADGRE2 Recombinant Protein

ADGRE2 (基因名), Adhesion G protein-coupled receptor E2 (蛋白名), agre2_human.

产品名称:

Human ADGRE2/ Adhesion G protein-coupled receptor E2 Recombinant Protein

货号:

R9373h

商标:

EIAab^®

监管等级:

RUO

别名:

EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2, CD312, EMR2

序列号:

Q9UHX3

来源:

E.coli

种属:

Human

标签:

His

序列:

261-390aa

预估分子量:

14.3 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human ADGRE2 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

Recombinant human ADGRE2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 19p13.12 by HGNC 19p13.12 by Entrez Gene 19p13.12 by Ensembl

ADGRE2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembrane moiety. Interacts with chondroitin sulfate; the interaction with chondroitin sulfate is calcium-dependent. Interacts with CD55.

功能:

Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins.

亚细胞位置:

Cell membrane Multi-pass membrane protein Cell projection Ruffle membrane Multi-pass membrane protein Localized at the leading edge of migrating cells.

数据库链接

UniGene:

Hs.531619

SMR:

Q9UHX3

STRING:

9606.ENSP00000472280

KEGG:

hsa:30817

MIM:

606100

Pfam:

PF00002

Uniprot:

Q9UHX3

相关产品

Dog ADGRE2 ELISA Kit

Dog ADGRE2 CLIA Kit

Dog ADGRE2 Protein

Dog ADGRE2 Polyclonal Antibody

Dog ADGRE2 Monoclonal Antibody

序列长度:

823

序列:

仅供参考，详细请咨询（services@eiaab.com）

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823:

TESEMHTLSS | SAKADTSKPS | TVN

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors."

(PMID: 25713288)

[2].

"Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function."

(PMID: 17928360)

[3].

"The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans."

(PMID: 12829604)

[4].

"The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells."

(PMID: 11994511)

[5].

"Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97."

(PMID: 10903844)

[6].

"Vibratory Urticaria Associated with a Missense Variant in ADGRE2."

(PMID: 26841242)

[7].

"Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains."

(PMID: 22310662)

[8].

"Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease."

(PMID: 20167235)

[9].

"Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55."

(PMID: 17449467)

[10].

"The role of receptor oligomerization in modulating the expression and function of leukocyte adhesion-G protein-coupled receptors."

(PMID: 17620333)

[1].

人ADGRE2重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人ADGRE2重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人ADGRE2重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人ADGRE2重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人ADGRE2重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人ADGRE2重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人ADGRE2重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人ADGRE2重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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