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AGAP1 (基因名), Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (蛋白名), agap1_human.
产品名称:

Human AGAP1/ Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Centaurin-gamma-2, GTP-binding and GTPase-activating protein 1, Cnt-g2, GGAP1, AGAP-1, CENTG2, KIAA1099

序列号:
Q9UPQ3
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human AGAP1 Protein
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Human AGAP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 2q37.2 by HGNC 2q37.2 by Entrez Gene 2q37.2 by Ensembl
AGAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Interacts with several subunits of the AP-3 protein complex: AP3M1, AP3S1 and AP3S2. Interacts with GUCY1A3 and GUCY1B3.


功能:
GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.


亚细胞位置:
Cytoplasm Associates with the endocytic compartment.


该产品尚未在任何出版物中被引用。

[1].
"Evaluation of the chromosome 2q37.3 gene CENTG2 as an autism susceptibility gene."

[2].
"The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3."

[3].
"AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase."

[4].
"AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton."

[5].
"Genome-wide association study identifies five new schizophrenia loci."
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