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ADAP1 (基因名), Arf-GAP with dual PH domain-containing protein 1 (蛋白名), adap1_human.
产品名称:

Human ADAP1/ Arf-GAP with dual PH domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Centaurin-alpha-1, Putative MAPK-activating protein PM25, Cnt-a1, CENTA1

序列号:
O75689
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ADAP1 Protein
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Human ADAP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 7p22.3 by HGNC 7p22.3 by Entrez Gene 7p22.3 by Ensembl
ADAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with PRKCA, PRKCI and PRKCZ. Interacts with the N-terminal region of PRKD1.


功能:
GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).


亚细胞位置:
Nucleus Cytoplasm Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.


该产品尚未在任何出版物中被引用。

[1].
"Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1."

[2].
"Molecular cloning and functional characterization of a human homologue of centaurin-alpha."

[3].
"Risk of meningioma and common variation in genes related to innate immunity."

[4].
"Polymorphisms in innate immunity genes and risk of childhood leukemia."

[5].
"Centaurin-alpha 1, an ADP-ribosylation factor 6 GTPase activating protein, inhibits beta 2-adrenoceptor internalization."

[6].
"p42(IP4)/centaurin alpha1, a brain-specific PtdIns(3,4,5)P3/Ins(1,3,4,5)P4-binding protein: membrane trafficking induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor."

[7].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins."

[10].
"Altered expression of protein p42IP4/centaurin-alpha 1 in Alzheimer's disease brains and possible interaction of p42IP4 with nucleolin."
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