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首页  >  重组蛋白  >  Human GOT1 Recombinant Protein
GOT1 (基因名), Aspartate aminotransferase, cytoplasmic (蛋白名), AATC_HUMAN.
产品名称:

Human GOT1/ Aspartate aminotransferase, cytoplasmic Recombinant Protein
细胞质天冬氨酸转氨

货号:

R1214h

商标:
EIAab®
监管等级:
别名:

cAspAT, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, cCAT, Glutamate oxaloacetate transaminase 1, Transaminase A

来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human GOT1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q24.2 by HGNC 10q24.2 by Entrez Gene 10q24.2 by Ensembl
GOT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


Sub Unit:
Homodimer.


Function:
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.


Subcellular Location:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Properties of human liver cytosolic aspartate aminotransferase mRNAs generated by alternative polyadenylation site selection."

[2].
"Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels."

[3].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[4].
"The DNA sequence and comparative analysis of human chromosome 10."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Genetic homogeneity, high-resolution mapping, and mutation analysis of the urofacial (Ochoa) syndrome and exclusion of the glutamate oxaloacetate transaminase gene (GOT1) in the critical region as the disease gene."

[7].
"The amino acid sequence of cytosolic aspartate aminotransferase from human liver."

[8].
"Neither ischemic parenchymal volume nor severe grade complication correlate transient high transaminase elevation after liver resection."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma."
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