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首页  >  重组蛋白  >  Human SERPINA3 Recombinant Protein
SERPINA3 (基因名), Alpha-1-antichymotrypsin (蛋白名), AACT_HUMAN.
产品名称:

Human SERPINA3/ Alpha-1-antichymotrypsin Recombinant Protein
α1抗胰糜蛋白

货号:

R1015h

商标:
EIAab®
监管等级:
别名:

ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, AACT, GIG24, GIG25

来源:
E.coli
种属:
Human
标签:
His
序列:
114-303aa
预估分子量:
20.9 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human SERPINA3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
Human SERPINA3 Protein
Recombinant human SERPINA3 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 14q32.13 by HGNC 14q32.13 by Entrez Gene 14q32.13 by Ensembl
SERPINA3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


Sub Unit:
Interacts with DNAJC1.


Function:
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.


Subcellular Location:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Alpha-1 antichymotrypsin gene signal peptide a/t polymorphism and primary intracerebral hemorrhage."

[2].
"The alanine/threonine polymorphism of the alpha-1-antichymotrypsin (SERPINA3) gene and ruptured intracranial aneurysms in the Japanese population."

[3].
"Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer's disease."

[4].
"A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease."

[5].
"The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity."

[6].
"Distribution of plasma alpha 1-antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls."

[7].
"A linkage disequilibrium between genes at the serine protease inhibitor gene cluster on chromosome 14q32.1 is associated with Wegener's granulomatosis."

[8].
"alpha-1-Antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease."

[9].
"Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver."

[10].
"Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement."
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