AAAS (基因名), Aladin (蛋白名), AAAS_HUMAN.
产品名称:
Human AAAS/ Aladin Recombinant Protein
货号:
-
商标:
EIAab®
监管等级:
别名:
Adracalin, ADRACALA, GL003
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
基因位点
AAAS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
通用注释
Sub Unit:
Interacts with NDC1, the interaction is required for nuclear pore localization.
Function:
Plays a role in the normal development of the peripheral and central nervous system.
Subcellular Location:
Nucleus
Nuclear pore complex
数据库链接
验证序列:
该产品尚未在任何出版物中被引用。
[2].
"The nuclear pore complex protein ALADIN is anchored via NDC1 but not via POM121 and GP210 in the nuclear envelope."
[3].
"Molecular cloning and characterization of AAAS-V2, a novel splice variant of human AAAS."
[5].
"Triple A syndrome is caused by mutations in AAAS, a new WD-repeat protein gene."
[6].
"Triple A or Allgrove syndrome. A case report with ophthalmic abnormalities and a novel mutation in the AAAS gene."
[7].
"Tissue-specific expression and subcellular localization of ALADIN, the absence of which causes human triple A syndrome."
[8].
"The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes."
[9].
"Deficiency of ferritin heavy-chain nuclear import in triple a syndrome implies nuclear oxidative damage as the primary disease mechanism."
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