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首页  >  重组蛋白  >  Mouse A2m Recombinant Protein
A2m (基因名), Alpha-2-macroglobulin (蛋白名), A2M_MOUSE.
产品名称:

Mouse A2m/ Alpha-2-macroglobulin Recombinant Protein
α-2巨球蛋白

货号:

R1017m

商标:
EIAab®
监管等级:
别名:

Alpha-2-M, Pregnancy zone protein, Pzp

来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse A2m Protein
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Mouse A2m Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


Sub Unit:
N/A


Function:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.


Subcellular Location:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Human alpha2-macroglobulin: genotype-phenotype relation."

[2].
"Alpha-2 macroglobulin is genetically associated with Alzheimer disease."

[3].
"Cloning of the human alpha 2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site."

[4].
"Structure of the human alpha-2 macroglobulin gene and its promotor."

[5].
"Human alpha 2-macroglobulin gene is located on chromosome 12."

[6].
"Association between haplotype -88G/25G in A2M with Alzheimer's disease."

[7].
"Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection."

[8].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[9].
"Lack of interaction between LRP1 and A2M polymorphisms for the risk of Alzheimer disease."

[10].
"Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study."
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