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首页  >  重组蛋白  >  Pig HTR4 Recombinant Protein
HTR4 (基因名), 5-hydroxytryptamine receptor 4 (蛋白名), 5HT4R_PIG.
产品名称:

Pig HTR4/ 5-hydroxytryptamine receptor 4 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT-4, Serotonin receptor 4

来源:
E.coli
种属:
Pig
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Pig HTR4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
May interact with PATJ, MAGI2, MPP3, NOS1, SLC9A3R1, SEC23A and SNX27. May form a complex including SLC9A3R1 and EZR.


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.


Subcellular Location:
Cell membrane Multi-pass membrane protein Endosome Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Interacts (via C-terminus) with GRK5; this interaction is promoted by 5-HT (serotonin).


该产品尚未在任何出版物中被引用。

[1].
"Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia."

[2].
"Cloning, expression, and pharmacology of four human 5-hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus."

[3].
"Expression of serotonin receptor mRNAs in blood vessels."

[4].
"Association study of the serotoninergic system in migraine in the Spanish population."

[5].
"Lack of association between HTR4 gene polymorphisms and schizophrenia in case-control and family-based samples."
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