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HTR3B (基因名), 5-hydroxytryptamine receptor 3B (蛋白名), 5HT3B_HUMAN.
产品名称:

Human HTR3B/ 5-hydroxytryptamine receptor 3B Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT3-B, Serotonin receptor 3B

来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human HTR3B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 11q23.2 by HGNC 11q23.2 by Entrez Gene 11q23.2 by Ensembl
HTR3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


Sub Unit:
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.


Subcellular Location:
Cell membrane Multi-pass membrane protein Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.


该产品尚未在任何出版物中被引用。

[1].
"Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients."

[2].
"The 5-HT3B subunit is a major determinant of serotonin-receptor function."

[3].
"The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit."

[4].
"Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders."

[5].
"Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea."

[6].
"An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population."

[7].
"Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine."

[8].
"Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression."

[9].
"Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists."

[10].
"Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients."
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