027-59234612(+86)
EIAab
首页  >  重组蛋白  >  Rat Htr2c Recombinant Protein
Htr2c (基因名), 5-hydroxytryptamine receptor 2C (蛋白名), 5HT2C_RAT.
产品名称:

Rat Htr2c/ 5-hydroxytryptamine receptor 2C Recombinant Protein
5-HT-2C

货号:

R10285r

商标:
EIAab®
监管等级:
别名:

5-HT-2C, 5-hydroxytryptamine receptor 1C, 5-HT-1C, Serotonin receptor 2C, 5ht1c, Htr1c

来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Htr2c Protein
规格 & 价格: 登录.
×
Rat Htr2c Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


Sub Unit:
Interacts with MPDZ. Interacts with ARRB2.


Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and feeding behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.


Subcellular Location:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."

[2].
"A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome."

[3].
"Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder."

[4].
"Mutation screening and assessment of the effect of genetic variations on expression and RNA editing of serotonin receptor 2C in the human brain."

[5].
"Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 价格 ($) 小计 1 ($)
小计 2: $
triangle
规格 数量 价格 ($)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59759960(+86)
邮箱:sales@eiaab.com