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HTR1E (基因名), 5-hydroxytryptamine receptor 1E (蛋白名), 5HT1E_HUMAN.
产品名称:

Human HTR1E/ 5-hydroxytryptamine receptor 1E Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT-1E, S31, Serotonin receptor 1E

来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human HTR1E Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 6q14.3 by HGNC 6q14.3 by Entrez Gene 6q14.3 by Ensembl
HTR1E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


Sub Unit:
N/A


Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.


Subcellular Location:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype."

[2].
"Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor."

[3].
"Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase."

[4].
"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."

[5].
"Association study of the serotoninergic system in migraine in the Spanish population."

[6].
"A common variant in DRD3 receptor is associated with autism spectrum disorder."

[7].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[8].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."

[9].
"Genetic evaluation of the serotonergic system in chronic fatigue syndrome."

[10].
"Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations."
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