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Mpg (基因名), DNA-3-methyladenine glycosylase (蛋白名), 3MG_RAT.
产品名称:

Rat Mpg/ DNA-3-methyladenine glycosylase Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, ADPG, N-methylpurine-DNA glycosylase

来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Mpg Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
Binds MBD1. Binds SSBP1.


Function:
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.


Subcellular Location:
Cytoplasm Mitochondrion matrix Mitochondrion nucleoid Nucleus


该产品尚未在任何出版物中被引用。

[1].
"Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase."

[2].
"Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin."

[3].
"Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision."

[4].
"Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse."

[5].
"Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere."

[6].
"Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16."

[7].
"Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)."

[8].
"Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein."

[9].
"Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations."

[10].
"Variation within DNA repair pathway genes and risk of multiple sclerosis."
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