027-59234612(+86)
EIAab
首页  >  重组蛋白  >  Human GPC1 Recombinant Protein
GPC1 (基因名), Glypican-1 (蛋白名), 10702_EIAAB.
产品名称:

Human GPC1/ Glypican-1 Recombinant Protein
磷脂酰基醇蛋白聚糖1

货号:

R9038-1h

商标:
EIAab®
监管等级:
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human GPC1 Protein
规格 & 价格: 登录.
×
Human GPC1 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q37.3 by HGNC 2q37.3 by Entrez Gene 2q37.3 by Ensembl
GPC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


Sub Unit:
N/A


Function:
Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.


Subcellular Location:
Secreted glypican-1 Secreted Extracellular space


该产品尚未在任何出版物中被引用。

[1].
"Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1."

[2].
"The structural role of N-linked glycans on human glypican-1."

[3].
"Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women."

[4].
"S-Nitrosylation of secreted recombinant human glypican-1."

[5].
"A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype."

[6].
"Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma."

[7].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease."

[10].
"Glypican-1 is a vehicle for polyamine uptake in mammalian cells: a pivital role for nitrosothiol-derived nitric oxide."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 价格 ($) 小计 1 ($)
小计 2: $
triangle
规格 数量 价格 ($)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59759960(+86)
邮箱:sales@eiaab.com