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VANGL2 (基因名), Vang-like protein 2 (蛋白名), vang2_human.
产品名称:

VANGL2 Antibody

货号:

P15196Rb

商标:
EIAab®
监管等级:
别名:

Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, KIAA1215, STB1

序列号:
Q9ULK5
反应性:
human,mouse,rat
免疫原:
Recombinant human VANGL2 protein ( R15196h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human VANGL2 Polyclonal Antibody
规格 & 价格: cart
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Human VANGL2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of VANGL2 in human tonsil tissue,Samples were probed using a VANGL2 Polyclonal Antibody dilution at 1:100.
通用注释


亚单元:
Homodimer and heterodimer with VANGL1. Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction. Also interacts with the PDZ domains of MAGI3, SCRIB/SCRB1 and FZD3.


功能:
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。
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