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THBS4 (基因名), Thrombospondin-4 (蛋白名), tsp4_human.
产品名称:

THBS4 Antibody

货号:

P0244Rb-h

商标:
EIAab®
监管等级:
别名:

TSP4

序列号:
P35443
反应性:
human
免疫原:
Recombinant human THBS4 protein ( R0244h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cardiovascular
Human THBS4 Polyclonal Antibody
规格 & 价格: cart
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Human THBS4 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
THBS4 was detected in perfusion fixed frozen sections of mouse skeletal muscle using Anti- THBS4 Antibody.?
通用注释


亚单元:
Homopentamer; disulfide-linked. Interacts with PTBP3. Interacts with NOTCH1 (By similarity). Interacts (via EGF-like 3; calcium-binding domain) with ATF6 and facilitates its processing, activation and nuclear translocation.


功能:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.


亚细胞位置:
Endoplasmic reticulum Sarcoplasmic reticulum Secreted Secreted Extracellular space Secreted Extracellular space Extracellular matrix


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