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TPSB2 (基因名), Tryptase beta-2 (蛋白名), tryb2_human.

产品名称:

TPSB2 Antibody

货号:

P0258Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Tryptase II, Tryptase-2, TPS2

序列号:

P20231

反应性:

human

免疫原:

corresponding to a sequence mapping at the 31-275aa of P20231

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cell Biology

规格 & 价格:

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Human TPSB2 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical staining of human tonsil using TPSB2 polyclonal antibody at 1:100.

通用注释

亚单元:

Homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence of heparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When the concentration of active monomers is higher, they convert to active monomers and then to active tetramers. These monomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites in the tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitors eg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms a complex with SERPINB6.

功能:

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.

亚细胞位置:

Secreted Released from the secretory granules upon mast cell activation.

数据库链接

UniGene:

Hs.405479

SMR:

P20231

STRING:

9606.ENSP00000343577

KEGG:

hsa:64499

MIM: