首页 > 一抗 > RHOA Antibody

RHOA (基因名), Transforming protein RhoA (蛋白名), rhoa_human.

产品名称:

RHOA Antibody

货号:

P9513Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Rho cDNA clone 12, h12, ARH12, ARHA, RHO12

序列号:

P61586

反应性:

human, mouse, rat

免疫原:

Recombinant human RHOA protein ( R9513h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

关注

Human RHOA Polyclonal Antibody

邮箱 *

消息 *

Please 登录.

产品说明书

数据表:

MSDS:

在线询价

数据
文献
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

Immunohistochemical of paraffin-embedded human colon cancer using RHOA antibody at dilution of 1:20.

通用注释

亚单元:

Interacts with ARHGEF28 (By similarity). Binds PRKCL1, ROCK1 and ROCK2. Interacts with ARHGEF2, ARHGEF3, NET1 and RTKN. Interacts with PLCE1 and AKAP13. Interacts with DIAPH1 (PubMed:23325789). Interacts (in the constitutively activated, GTP-bound form) with DGKQ. Interacts with human respiratory syncytial virus (HRSV) protein F; this interaction facilitates virus-induced syncytium formation. Interacts with RACK1; enhances RHOA activation. Interacts with PKP4; the interaction is detected at the midbody. Interacts (GTP-bound form preferentially) with PKN2; the interaction stimulates autophosphorylation and phosphorylation of PKN2. Interacts with ARHGDIA; this interaction inactivates and stabilizes RHOA. Interacts with ARHGDIB. Interacts (GTP-bound form) with KCNA2 (via cytoplasmic N-terminal domain) (PubMed:9635436).

功能:

(Microbial infection) Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders.

亚细胞位置:

Cell membrane Lipid-anchor Cytoplasmic side Cytoplasm Cytoskeleton Cleavage furrow Cytoplasm Cell cortex Midbody Cell projection Lamellipodium Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in a activated form and in a myosin- and actin-independent manner.

数据库链接

UniGene:

Hs.247077

SMR:

P61586

STRING:

9606.ENSP00000400175

KEGG:

hsa:387

MIM:

165390

Pfam: