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HRAS (基因名), GTPase HRas (蛋白名), rash_human.

产品名称:

HRAS Antibody

货号:

P1294Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, HRAS1

序列号:

P01112

反应性:

human

免疫原:

corresponding to a sequence mapping at the 1-186aa of P01112

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cancer

规格 & 价格:

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Human HRAS Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with HRAS antibody.

通用注释

亚单元:

In its GTP-bound form interacts with PLCE1 (PubMed:11022048). Interacts with TBC1D10C (PubMed:17230191). Interacts with RGL3 (By similarity). Interacts with HSPD1 (By similarity). Found in a complex with at least BRAF, HRAS, MAP2K1, MAPK3 and RGS14 (By similarity). Interacts (active GTP-bound form) with RGS14 (via RBD 1 domain) (By similarity). Forms a signaling complex with RASGRP1 and DGKZ (PubMed:11257115). Interacts with RASSF5 (PubMed:18596699). Interacts with PDE6D (PubMed:11980706). Interacts with IKZF3 (PubMed:10369681). Interacts with RACK1 (PubMed:14500341). Interacts with PIK3CG; the interaction is required for membrane recruitment and beta-gamma G protein dimer-dependent activation of the PI3K gamma complex PIK3CG:PIK3R6 (By similarity). Interacts with RAPGEF2 (PubMed:10608844, PubMed:11598133).

功能:

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

亚细胞位置:

Isoform 2 Nucleus Cytoplasm Cytoplasm Perinuclear region Colocalizes with RACK1 to the perinuclear region.

数据库链接

UniGene:

Hs.37003

SMR:

P01112

STRING:

9606.ENSP00000309845

KEGG: