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ENTPD5 (基因名), Ectonucleoside triphosphate diphosphohydrolase 5 (蛋白名), entp5_human.
产品名称:

ENTPD5 Antibody

货号:

P1978Rb-h

商标:
EIAab®
监管等级:
别名:

CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, GDPase ENTPD5, UDPase ENTPD5, NTPDase 5, CD39L4, PCPH

序列号:
O75356
反应性:
human
免疫原:
Recombinant human ENTPD5 protein ( R1978h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human ENTPD5 Polyclonal Antibody
规格 & 价格: cart
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Human ENTPD5 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry-Paraffin:ENTPD5 Antibody- Staining of human liver shows high expression.
通用注释


亚单元:
Exists both as a monomer and a disulfide-linked homodimer, the dimers are enzymatically inactive.


功能:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.


亚细胞位置:
Endoplasmic reticulum Secreted


该产品尚未在任何出版物中被引用。
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