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Enpp2 (基因名), Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (蛋白名), enpp2_mouse.
产品名称:

Enpp2 Antibody

货号:

P1228Rb-m

商标:
EIAab®
监管等级:
别名:

Autotaxin, Extracellular lysophospholipase D, LysoPLD, E-NPP 2, Npps2, Pdnp2

序列号:
Q9R1E6
反应性:
MOUSE
免疫原:
corresponding to a sequence mapping at the 597-862aa of Q9R1E6
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
推荐产品:
研究领域:
Cardiovascular
  • Mouse Enpp2 Polyclonal Antibody
  • Mouse Enpp2 Polyclonal Antibody
  • Mouse Enpp2 Polyclonal Antibody
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Mouse Enpp2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Mouse Enpp2 Polyclonal Antibody
293T cells lysate was subjected to SDS-PAGE followed by Western Blot with Enpp2(Mouse) antibody at dilution of 1:400
Immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by ENPP2 antibody.
通用注释


亚单元:
N/A


功能:
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.


亚细胞位置:
Secreted Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells (By similarity).


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