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CFLAR (基因名), CASP8 and FADD-like apoptosis regulator (蛋白名), cflar_human.
产品名称:

CFLAR Antibody

货号:

P15094Rb-h

商标:
EIAab®
监管等级:
别名:

Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, Inhibitor of FLICE, MACH-related inducer of toxicity, Usurpin, CASH, Casper, CLARP, c-FLIP, FLAME-1, I-FLICE, MRIT, CASH, CASP8AP1, CLARP, MRIT

序列号:
O15519
反应性:
human
免疫原:
Recombinant human CFLAR protein ( R15094h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human CFLAR Polyclonal Antibody
规格 & 价格: cart
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Human CFLAR Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human Pancreas (formalin-fixed, paraffin-embedded) stained with CFLAR antibody at 2.5 ug/ml
通用注释


亚单元:
TNFRSF6 stimulation triggers recruitment to the death-inducing signaling complex (DISC) formed by TNFRSF6, FADD and caspase-8. A proteolytic fragment (p43) stays associated with the DISC. Also interacts with caspase-10, caspase-3, TRAF1, TRAF2 and Bcl-X(L) (in vitro). Interacts with HBV protein X.


功能:
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.


亚细胞位置:
N/A


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