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CEBPA (基因名), CCAAT/enhancer-binding protein alpha (蛋白名), cebpa_human.

产品名称:

CEBPA Antibody

货号:

P0712Rb

商标:

EIAab^®

监管等级:

RUO

别名:

C/EBP alpha, CEBP

序列号:

P49715

反应性:

human,mouse,rat

免疫原:

Recombinant human CEBPA protein ( R0712h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human CEBPA Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

CEBPA antibody immunohistochemistry analysis in formalin fixed and paraffin embedded Human Mammary Cancer Tissue.

通用注释

亚单元:

Binds DNA as a homodimer and as a heterodimer. Can form stable heterodimers with CEBPB, CEBPD, CEBPE and CEBPG (By similarity). Interacts with PRDM16 (By similarity). Interacts with UBN1 (PubMed:10725330). Interacts with ZNF638; this interaction increases transcriptional activation (By similarity). Interacts with the complex TFDP2:E2F1; the interaction prevents CEBPA binding to target gene promoters and represses its transcriptional activity (PubMed:20176812). Interacts with RB1 (PubMed:15107404). Interacts (when phosphorylated at SER-190) with CDK2, CDK4, E2F4 and SMARCA2 (PubMed:15107404). Interacts with SREBPF1 (By similarity). Interacts with FOXO1 (via the Fork-head domain); the interaction increases when FOXO1 is deacetylated (By similarity). Isoform 1 and isoform 4 interacts with TAF1A and UBTF (PubMed:20075868). Isoform 4 interacts with NPM1 (PubMed:20075868). Interacts with HBV protein X (PubMed:9915821). Interacts (via recognition sequence) with TRIB1 (PubMed:20410507, PubMed:26455797).

功能:

Isoform 4: Directly and specifically enhances ribosomal DNA transcription interacting with RNA polymerase I-specific cofactors and inducing histone acetylation.

亚细胞位置:

Isoform 4 Nucleus Nucleolus

数据库链接

UniGene:

Hs.76171

SMR:

P49715

STRING:

9606.ENSP00000427514

KEGG:

hsa:1050

MIM: