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Znf423 (基因名), Zinc finger protein 423 (蛋白名), zn423_rat.
产品名称:

Rat Znf423/ Zinc finger protein 423 ELISA Kit

货号:

E4972r

商标:
EIAab®
监管等级:
别名:

Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, rOAZ, Oaz, Zfp423

检测方法:
ELISA
特异性:
Natural and recombinant rat Zinc finger protein 423
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Znf423 ELISA Kit
规格 & 价格: cart
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Rat Znf423 ELISA Kit
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通用注释


亚单元:
Homodimer. Interacts with PARP1, SMAD1 and SMAD4 (By similarity). Interacts with EBF1. Interacts with CEP290.


功能:
Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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