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Ubr4 (基因名), E3 ubiquitin-protein ligase UBR4 (蛋白名), ubr4_mouse.
产品名称:

Mouse Ubr4/ E3 ubiquitin-protein ligase UBR4 ELISA Kit
E3泛素连接酶UBR4

货号:

E0192m

商标:
EIAab®
监管等级:
别名:

N-recognin-4, RING-type E3 ubiquitin transferase UBR4, Zinc finger UBR1-type protein 1, p600, Kiaa0462, Zubr1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.078ng/mL
特异性:
Natural and recombinant mouse E3 ubiquitin-protein ligase UBR4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Ubr4 ELISA Kit
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Mouse Ubr4 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with RB1 and calmodulin.


功能:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.


亚细胞位置:
Membrane Multi-pass membrane protein Cytoplasm Cytoplasm Cytoskeleton Nucleus Concentrates at the leading edge of membrane structures involved in actin motility.


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