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USP11 (基因名), Ubiquitin carboxyl-terminal hydrolase 11 (蛋白名), ubp11_canlf.
产品名称:

Dog USP11/ Ubiquitin carboxyl-terminal hydrolase 11 ELISA Kit

货号:

E14283d

商标:
EIAab®
监管等级:
别名:

Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11

检测方法:
ELISA
特异性:
Natural and recombinant dog Ubiquitin carboxyl-terminal hydrolase 11
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Dog USP11 ELISA Kit
规格 & 价格: cart
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Dog USP11 ELISA Kit
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通用注释


亚单元:
Monomer. Interacts with RANBP9/RANBPM. Interacts with BRCA2. Interacts with CHUK/IKKA. Interacts with NFKBIA. Associated component of the Polycomb group (PcG) multiprotein PRC1-like complex.


功能:
Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like complex.


亚细胞位置:
Nucleus Cytoplasm Chromosome Predominantly nuclear. Associates with chromatin.


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