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Trpc4 (基因名), Short transient receptor potential channel 4 (蛋白名), trpc4_rat.
产品名称:

Rat Trpc4/ Short transient receptor potential channel 4 ELISA Kit

货号:

E12157r

商标:
EIAab®
监管等级:
别名:

Capacitative calcium entry channel 1, CCE1, Trp4

检测方法:
ELISA
特异性:
Natural and recombinant rat Short transient receptor potential channel 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Rat Trpc4 ELISA Kit
规格 & 价格: cart
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Rat Trpc4 ELISA Kit
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亚单元:
Homotetramer and heterotetramer with TRPC1 and/or TRPC5. Heteromers containing TRPC3 or TRPC6 are also found exclusively in embryonic brain. Isoform alpha but not isoform beta associates with inositol 1,4,5-trisphosphate receptor (ITPR). Interacts with NHERF (By similarity). Interacts with MX1 and RNF24 (By similarity). Interacts (via CIRB domain) with SESTD1 (via the spectrin 1 repeat) and SPTBN5 (via C-terminus) (By similarity). Interacts with CDH5 and CTNNB1 (By similarity). Interacts (via protein 4.1-binding domain) with EPB41L2 (By similarity). Interacts with TRPC4AP.


功能:
Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.


亚细胞位置:
Membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


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