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Ngfr (基因名), Tumor necrosis factor receptor superfamily member 16 (蛋白名), tnr16_rat.
产品名称:

Rat Ngfr/ Tumor necrosis factor receptor superfamily member 16 ELISA Kit
肿瘤坏死因子受体超家族成员16

货号:

E9231r

商标:
EIAab®
监管等级:
别名:

Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, p75 ICD, NGF receptor, CD271, Tnfrsf16

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.078ng/mL
特异性:
Natural and recombinant rat Tumor necrosis factor receptor superfamily member 16
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Rat Ngfr ELISA Kit
规格 & 价格: cart
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Rat Ngfr ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

107-116%

100-110%

97-106%

100-110%

EDTA plasma(n=5)

95-107%

105-115%

100-110%

103-113%

heparin plasma(n=5)

113-123%

 

97-97%

99-109%

105-114%

 

通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with RTN4R (By similarity). Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of NGFR and NTRK1. Interacts (via death domain) with RAB31. Interacts with NTRK2; may regulate the ligand specificity of the NTRK2 receptor. Interacts with LINGO1 and NRADD. Interacts with MAGED1; the interaction antagonizes the association NGFR:NTRK1.


功能:
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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