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TFRC (基因名), Transferrin receptor protein 1 (蛋白名), tfr1_pig.
产品名称:

Pig TFRC/ Transferrin receptor protein 1 ELISA Kit
转铁蛋白受体蛋白1

货号:

E0809p

商标:
EIAab®
监管等级:
别名:

CD71, TR

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
1.56-100ng/mL
灵敏度:
0.29ng/mL
特异性:
Natural and recombinant pig Transferrin receptor protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Pig TFRC ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

100-108%

102-111%

112-122%

83-92%

EDTA plasma(n=5)

82-92%

98-108%

111-120%

107-116%

heparin plasma(n=5)

80-90%

 

87-96%

108-120%

110-122%

 

通用注释


亚单元:
Homodimer; disulfide-linked. Binds one transferrin or HFE molecule per subunit. Interacts with SH3BP4 (By similarity). Interacts with SH3BP3. Interacts with STEAP3; facilitates TFRC endocytosis in erythroid precursor cells.


功能:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake.


亚细胞位置:
Cell membrane Single-pass type II membrane protein Melanosome


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