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TFIP11 (基因名), Tuftelin-interacting protein 11 (蛋白名), tfp11_pig.
产品名称:

Pig TFIP11/ Tuftelin-interacting protein 11 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Septin and tuftelin-interacting protein 1, STIP-1, STIP

检测方法:
ELISA
特异性:
Natural and recombinant pig Tuftelin-interacting protein 11
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig TFIP11 ELISA Kit
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Pig TFIP11 ELISA Kit
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通用注释


亚单元:
Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.


功能:
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.


亚细胞位置:
Cytoplasm Nucleus In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles.


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