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Tcf3 (基因名), Transcription factor E2-alpha (蛋白名), tfe2_mouse.
产品名称:

Mouse Tcf3/ Transcription factor E2-alpha ELISA Kit
转录因子E2-alpha

货号:

E14975m

商标:
EIAab®
监管等级:
别名:

Immunoglobulin enhancer-binding factor E12/E47, Transcription factor 3, Transcription factor A1, TCF-3, Alf2, Me2, Tcfe2a

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant mouse Transcription factor E2-alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Mouse Tcf3 ELISA Kit
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Mouse Tcf3 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: 0
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 0
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

80

80-80

Plasma

80

80-80

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

93-105%

105-113%

87-99%

103-112%

EDTA plasma(n=5)

95-104%

102-112%

99-109%

106-116%

heparin plasma(n=5)

101-113%

 

93-102%

111-121%

106-118%

 

通用注释


亚单元:
Forms a heterodimer with TWIST2. Forms a heterodimer with NEUROD1; the heterodimer is inhibited in presence of ID2, but not NR0B2, to E-box element. Isoform E12 interacts with RALGAPA1 and FIGLA. Interacts with EP300. Efficient DNA binding requires dimerization with another bHLH protein (By similarity). Homodimer. Heterodimer. Forms a heterodimer with MYOG; heterodimerization enhances MYOG DNA-binding and transcriptional activities. Interacts with PTF1A, TGFB1I1 and UBE2I. Component of a nuclear TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3. Interacts with NEUROD2. Interacts with BHLHA9. Forms a heterodimer with ATOH8; repress transcription of TCF3 and TCF3/NEUROG3 dimer-induced transactivation of E box-dependent promoters.


功能:
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.


亚细胞位置:
Nucleus


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