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Taf1c (基因名), TATA box-binding protein-associated factor, RNA polymerase I, subunit C (蛋白名), taf1c_rat.
产品名称:

Rat Taf1c/ TATA box-binding protein-associated factor, RNA polymerase I, subunit C ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

TATA box-binding protein-associated factor 1C, Transcription initiation factor SL1/TIF-IB subunit C, TBP-associated factor 1C

检测方法:
ELISA
特异性:
Natural and recombinant rat TATA box-binding protein-associated factor, RNA polymerase I, subunit C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Taf1c ELISA Kit
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Rat Taf1c ELISA Kit
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通用注释


亚单元:
Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with MYC and RRN3. Interacts with p53/TP53; the interaction prevents the association of SL1/TIF-IB with UBTF and represses RNA polymerase I transcription.


功能:
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.


亚细胞位置:
Nucleus


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