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SIRT5 (基因名), NAD-dependent protein deacylase sirtuin-5, mitochondrial (蛋白名), sir5_canfa.
产品名称:

Dog SIRT5/ NAD-dependent protein deacylase sirtuin-5, mitochondrial ELISA Kit
沉默调节蛋白5

货号:

E11384d

商标:
EIAab®
监管等级:
别名:

Regulatory protein SIR2 homolog 5, SIR2-like protein 5

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant dog NAD-dependent protein deacylase sirtuin-5, mitochondrial
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Dog SIRT5 ELISA Kit
规格 & 价格: cart
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Dog SIRT5 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

102-112%

107-116%

82-93%

96-106%

EDTA plasma(n=5)

84-93%

96-106%

103-115%

86-98%

heparin plasma(n=5)

90-100%

 

113-123%

91-103%

107-117%

 

通用注释


亚单元:
Monomer. Homodimer. Interacts with CPS1.


功能:
NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.


亚细胞位置:
Mitochondrion Cytoplasm Cytosol Nucleus Mainly mitochondrial. Also present extramitochondrially: a fraction is present in the cytosol and very small amounts are also detected in the nucleus.


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