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SELENOS (基因名), Selenoprotein S (蛋白名), sels_bovin.
产品名称:

Bovine SELENOS/ Selenoprotein S ELISA Kit
硒蛋白S

货号:

E10141b

商标:
EIAab®
监管等级:
别名:

SelS

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/ml
灵敏度:
0.081ng/ml
特异性:
Natural and recombinant bovine Selenoprotein S
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Bovine SELENOS ELISA Kit
规格 & 价格: cart
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Bovine SELENOS ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with DERL1 and (via VIM motif) with VCP, suggesting that it forms a membrane complex with DERL1 that serves as a receptor for VCP. Also interacts with DERL2, DERL3 and SELENOK. The SELENOK-SELENOS complex interacts with VCP. Part of a complex which includes CANX, DERL1, DERL2, DDOST/OST48, RPN1, RPN2, SELENOK, STT3A, VCP AND SELENOS.


功能:
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Cytoplasm


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