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SCN9A (基因名), Sodium channel protein type 9 subunit alpha (蛋白名), scn9a_human.
产品名称:

Human SCN9A/ Sodium channel protein type 9 subunit alpha ELISA Kit
钠通道蛋白9亚基α

货号:

E15345h

商标:
EIAab®
监管等级:
别名:

Neuroendocrine sodium channel, Peripheral sodium channel 1, Sodium channel protein type IX subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.7, hNE-Na, PN1, NENA

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.091ng/mL
特异性:
Natural and recombinant human Sodium channel protein type 9 subunit alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human SCN9A ELISA Kit
规格 & 价格: cart
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Human SCN9A ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
The sodium channel complex consists of a large, channel-forming alpha subunit and 2-3 smaller, ancillary beta subunits (PubMed:7720699, PubMed:17167479, PubMed:25240195). Interacts with NEDD4 and NEDD4L (By similarity). Interacts with the conotoxin GVIIJ (PubMed:24497506).


功能:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na(+) channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).


亚细胞位置:
Cell membrane Multi-pass membrane protein Cell projection In neurite terminals.


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