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SLC22A1 (基因名), Solute carrier family 22 member 1 (蛋白名), s22a1_pig.
产品名称:

Pig SLC22A1/ Solute carrier family 22 member 1 ELISA Kit
溶质载体家族22成员1

货号:

E15326p

商标:
EIAab®
监管等级:
别名:

Organic cation transporter 1, pOCT1, OCT1

检测方法:
ELISA
特异性:
Natural and recombinant pig Solute carrier family 22 member 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig SLC22A1 ELISA Kit
规格 & 价格: cart
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Pig SLC22A1 ELISA Kit
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产品说明书
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通用注释


亚单元:
N/A


功能:
Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.


亚细胞位置:
Basolateral cell membrane Multi-pass membrane protein


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