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RSAD2 (基因名), Radical S-adenosyl methionine domain-containing protein 2 (蛋白名), rsad2_bovin.
产品名称:

Bovine RSAD2/ Radical S-adenosyl methionine domain-containing protein 2 ELISA Kit
含蛋白2激进的S-腺苷甲硫氨酸域

货号:

E3787b

商标:
EIAab®
监管等级:
别名:

Viperin, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
15.6-1000pg/mL
灵敏度:
7.65pg/mL
特异性:
Natural and recombinant bovine Radical S-adenosyl methionine domain-containing protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Bovine RSAD2 ELISA Kit
规格 & 价格: cart
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Bovine RSAD2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer. Interacts (via C-terminus) with VAPA/VAP33 (via C-terminus) and inhibits its interaction with hepatitis virus C (HCV) protein NS5A. Interacts with HADHB, IRAK1 and TRAF6.


功能:
Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphosphate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cell activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.


亚细胞位置:
Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Lipid droplet


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