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RB1 (基因名), Retinoblastoma-associated protein (蛋白名), rb_chick.
产品名称:

Chicken RB1/ Retinoblastoma-associated protein ELISA Kit

货号:

E15639c

商标:
EIAab®
监管等级:
别名:

p104, pRb, Rb

检测方法:
ELISA
特异性:
Natural and recombinant chicken Retinoblastoma-associated protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Chicken RB1 ELISA Kit
规格 & 价格: cart
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Chicken RB1 ELISA Kit
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产品说明书
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通用注释


亚单元:
Interacts with and sequesters the E2F1 transcription factor. Interacts with SUV39H1, KMT5B and KMT5C (By similarity). Interacts with, and is inhibited by fowl adenovirus 1 protein GAM-1.


功能:
Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting chromatin-modifying enzymes to promoters.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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