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RAB43 (基因名), Ras-related protein Rab-43 (蛋白名), rab43_human.
产品名称:

Human RAB43/ Ras-related protein Rab-43 ELISA Kit

货号:

E6517h

商标:
EIAab®
监管等级:
别名:

Ras-related protein Rab-41, RAB41

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
22pg/mL
特异性:
Natural and recombinant human Ras-related protein Rab-43
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human RAB43 ELISA Kit
规格 & 价格: cart
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Human RAB43 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
N/A


功能:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.


亚细胞位置:
Cytoplasmic vesicle Phagosome Cytoplasmic vesicle Phagosome membrane Lipid-anchor Cytoplasmic side Golgi apparatus Golgi apparatus Trans-Golgi network membrane Lipid-anchor Golgi apparatus Trans-Golgi network Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).


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