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RAB25 (基因名), Ras-related protein Rab-25 (蛋白名), rab25_bovin.
产品名称:

Bovine RAB25/ Ras-related protein Rab-25 ELISA Kit

货号:

E4724b

商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant bovine Ras-related protein Rab-25
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine RAB25 ELISA Kit
规格 & 价格: cart
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通用注释


亚单元:
Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Interacts (via the hypervariable C-terminal region) with ITGB1 (via the cytoplasmic region); the interaction is GTP-dependent. Interacts with ITGAV. Associates with the integrin alpha-V/beta-1 heterodimer.


功能:
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis.


亚细胞位置:
Cell membrane Lipid-anchor Cytoplasmic side Cell projection Pseudopodium membrane Cytoplasmic vesicle Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips.


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